# Best 15 Microsoft Defender for Office 365 Alternatives in 2026 - Software Advice > Find the top Microsoft Defender for Office 365 Software alternatives in 2026. Our list is fueled by product features and real user reviews and ratings. Compare these alternatives to make sure you are picking the best Email Security Software for your business. Source: https://www.softwareadvice.com/anti-spam/microsoft-defender-for-office-365-profile/alternatives --- [Home](https://www.softwareadvice.com/) / [Email Security Software](https://www.softwareadvice.com/email-security/) / [Microsoft Defender for Office 365](https://www.softwareadvice.com/anti-spam/microsoft-defender-for-office-365-profile/) / Microsoft Defender for Office 365 Alternatives Software Advice offers objective insights based on verified user reviews and independent product and market research. When our advisors match you to a software provider, we may earn a referral fee. [Overview](https://www.softwareadvice.com/anti-spam/microsoft-defender-for-office-365-profile/)[Reviews](https://www.softwareadvice.com/anti-spam/microsoft-defender-for-office-365-profile/reviews/) Alternatives # Best 15 Microsoft Defender for Office 365 Alternatives Microsoft Defender for Office 365 4.6 [(238)](https://www.softwareadvice.com/anti-spam/microsoft-defender-for-office-365-profile/reviews/) Pricing: Available upon request Free trial Free version On this page - Popular Alternatives - Alternatives - Popular Comparisons ## Preview of Top Microsoft Defender for Office 365 Alternatives Main Product Microsoft Defender for Office 365 4.6 [(238)](https://www.softwareadvice.com/anti-spam/microsoft-defender-for-office-365-profile/reviews/) Ratings Breakdown - 4.54Ease of use - 4.48Value for money - 4.30Customer support - 4.49Functionality Pricing Available upon request Top Alternative Hoxhunt 4.9 [(338)](https://www.softwareadvice.com/email-security/hoxhunt-profile/reviews/) Ratings Breakdown - 4.93Ease of use - 4.77Value for money - 4.82Customer support - 4.83Functionality Pricing Available upon request Top Alternative Trustifi 5.0 [(20)](https://www.softwareadvice.com/email-security/trustifi-profile/#reviews) Ratings Breakdown - 4.75Ease of use - 4.89Value for money - 4.94Customer support - 4.80Functionality Pricing Starting at $6.00 per month Top Alternative Libraesva Email Security 4.9 [(50)](https://www.softwareadvice.com/secure-email-gateway/libraesva-email-security-profile/#reviews) Ratings Breakdown - 4.78Ease of use - 4.85Value for money - 4.88Customer support - 4.84Functionality Pricing Starting at £5.00 per year Top Alternative SpamTitan 4.6 [(563)](https://www.softwareadvice.com/secure-email-gateway/spamtitan-profile/reviews/) Ratings Breakdown - 4.43Ease of use - 4.50Value for money - 4.53Customer support - 4.41Functionality Pricing Starting at $1.26 per month Top Alternative Proton Mail 4.5 [(122)](https://www.softwareadvice.com/email-security/protonmail-profile/reviews/) Ratings Breakdown - 4.43Ease of use - 4.26Value for money - 4.03Customer support - 4.31Functionality Pricing Starting at $6.99 per month ## Microsoft Defender for Office 365 Alternatives [### Hoxhunt](https://www.softwareadvice.com/email-security/hoxhunt-profile/) 4.9 [(338)](https://www.softwareadvice.com/email-security/hoxhunt-profile/reviews/) Pricing: Available upon request Free trial Free version Pricing: Available upon request Free trial Free version ### Features Comparison 81% Unique Features for Hoxhunt - Activity Dashboard - Alerts/Notifications - Assessment Management See All 19% Shared Features with Microsoft Defender for Office 365 - Alerts/Escalation - Email Filtering - Phishing Protection See All ### Integrations Comparison 100% Unique Integrations for Hoxhunt - Gmail - Microsoft Outlook 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Hoxhunt Screenshots [### Trustifi](https://www.softwareadvice.com/email-security/trustifi-profile/) 5.0 [(20)](https://www.softwareadvice.com/email-security/trustifi-profile/#reviews) Starting Price: $6.00 per month Free trial Free version Starting Price: $6.00 per month Free trial Free version ### Features Comparison 71% Unique Features for Trustifi - Anti Virus - API - Archiving & Retention See All 29% Shared Features with Microsoft Defender for Office 365 - Alerts/Escalation - Allow/Block List - Email Attachment Protection See All ### Integrations Comparison 100% Unique Integrations for Trustifi - Amazon S3 - Google Workspace - Microsoft Exchange See All 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Trustifi Screenshots [### Libraesva Email Security](https://www.softwareadvice.com/secure-email-gateway/libraesva-email-security-profile/) 4.9 [(50)](https://www.softwareadvice.com/secure-email-gateway/libraesva-email-security-profile/#reviews) Starting Price: £5.00 per year Free trial Free version Starting Price: £5.00 per year Free trial Free version ### Features Comparison 72% Unique Features for Libraesva Email Security - AI/Machine Learning - Anomaly/Malware Detection - API See All 28% Shared Features with Microsoft Defender for Office 365 - Email Attachment Protection - Email Filtering - Phishing Protection See All ### Integrations Comparison 0% Unique Integrations for Libraesva Email Security - No unique integrations 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Libraesva Email Security Screenshots [### SpamTitan](https://www.softwareadvice.com/secure-email-gateway/spamtitan-profile/) 4.6 [(563)](https://www.softwareadvice.com/secure-email-gateway/spamtitan-profile/reviews/) Starting Price: $1.26 per month Free trial Free version Starting Price: $1.26 per month Free trial Free version ### Features Comparison 81% Unique Features for SpamTitan - Access Controls/Permissions - Activity Dashboard - Activity Tracking See All 19% Shared Features with Microsoft Defender for Office 365 - Allow/Block List - Email Attachment Protection - Email Filtering See All ### Integrations Comparison 100% Unique Integrations for SpamTitan - Microsoft 365 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See SpamTitan Screenshots [### Proton Mail](https://www.softwareadvice.com/email-security/protonmail-profile/) 4.5 [(122)](https://www.softwareadvice.com/email-security/protonmail-profile/reviews/) Starting Price: $6.99 per month Free trial Free version Starting Price: $6.99 per month Free trial Free version ### Features Comparison 55% Unique Features for Proton Mail - Email Management - Encryption - Remote Access/Control See All 45% Shared Features with Microsoft Defender for Office 365 - Email Attachment Protection - Email Filtering - Spam Blocker See All ### Integrations Comparison 100% Unique Integrations for Proton Mail - Microsoft Outlook - Postbox - Proton Drive See All 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Proton Mail Screenshots [### ESET Endpoint Security](https://www.softwareadvice.com/security/eset-endpoint-security-profile/) 4.7 [(1169)](https://www.softwareadvice.com/security/eset-endpoint-security-profile/reviews/) Starting Price: A$304.00 per year Free trial Free version Starting Price: A$304.00 per year Free trial Free version ### Features Comparison 92% Unique Features for ESET Endpoint Security - Access Controls/Permissions - Activity Dashboard - Activity Monitoring See All 8% Shared Features with Microsoft Defender for Office 365 - Policy Management - Real-Time Monitoring - Threat Protection See All ### Integrations Comparison 100% Unique Integrations for ESET Endpoint Security - Autotask PSA - Axonius - Blumira See All 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See ESET Endpoint Security Screenshots [### Proofpoint Email Protection](https://www.softwareadvice.com/security/proofpoint-email-protection-profile/) 4.2 [(45)](https://www.softwareadvice.com/security/proofpoint-email-protection-profile/reviews/) Pricing: Available upon request Free trial Free version Pricing: Available upon request Free trial Free version ### Features Comparison 77% Unique Features for Proofpoint Email Protection - Activity Dashboard - Anomaly/Malware Detection - Anti Spam See All 23% Shared Features with Microsoft Defender for Office 365 - Email Filtering - Phishing Protection - Policy Management See All ### Integrations Comparison 0% Unique Integrations for Proofpoint Email Protection - No unique integrations 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Proofpoint Email Protection Screenshots [### Topsec Cloud Solutions](https://www.softwareadvice.com/email-archiving/blockmail-profile/) 4.9 [(69)](https://www.softwareadvice.com/email-archiving/blockmail-profile/#reviews) Starting Price: €12.00 per year Free trial Free version Starting Price: €12.00 per year Free trial Free version ### Features Comparison 56% Unique Features for Topsec Cloud Solutions - Activity Dashboard - Archiving & Retention - Audit Trail See All 44% Shared Features with Microsoft Defender for Office 365 - Alerts/Escalation - Allow/Block List - Email Attachment Protection See All ### Integrations Comparison 100% Unique Integrations for Topsec Cloud Solutions - Google Workspace - Microsoft 365 - Microsoft Outlook See All 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Topsec Cloud Solutions Screenshots [### MimeCast Email Security](https://www.softwareadvice.com/marketing/mimecast-email-security-profile/) 4.3 [(80)](https://www.softwareadvice.com/marketing/mimecast-email-security-profile/reviews/) Pricing: Available upon request Free trial Free version Pricing: Available upon request Free trial Free version ### Features Comparison 71% Unique Features for MimeCast Email Security - Activity Dashboard - Anomaly/Malware Detection - Anti Virus See All 29% Shared Features with Microsoft Defender for Office 365 - Email Attachment Protection - Email Filtering - Real-Time Monitoring See All ### Integrations Comparison 0% Unique Integrations for MimeCast Email Security - No unique integrations 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See MimeCast Email Security Screenshots [### Keepnet Labs](https://www.softwareadvice.com/incident-management/keepnet-labs-profile/) 5.0 [(46)](https://www.softwareadvice.com/incident-management/keepnet-labs-profile/#reviews) Pricing: Available upon request Free trial Free version Pricing: Available upon request Free trial Free version ### Features Comparison 87% Unique Features for Keepnet Labs - Activity Dashboard - Alerts/Notifications - Anomaly/Malware Detection See All 13% Shared Features with Microsoft Defender for Office 365 - Email Attachment Protection - Email Filtering - Phishing Protection See All ### Integrations Comparison 100% Unique Integrations for Keepnet Labs - IBM QRadar Incident Forensics - Microsoft Entra ID - Splunk Enterprise 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Keepnet Labs Screenshots [### Graphus](https://www.softwareadvice.com/anti-spam/graphus-profile/) 4.3 [(27)](https://www.softwareadvice.com/anti-spam/graphus-profile/reviews/) Starting Price: $3.00 per month Free trial Free version Starting Price: $3.00 per month Free trial Free version ### Features Comparison 54% Unique Features for Graphus - Email Routing - Encryption - Greylisting See All 46% Shared Features with Microsoft Defender for Office 365 - Allow/Block List - Email Attachment Protection - Phishing Protection See All ### Integrations Comparison 0% Unique Integrations for Graphus - No unique integrations 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Graphus Screenshots [### McAfee Security for Email Servers](https://www.softwareadvice.com/anti-spam/mcafee-security-for-email-servers-profile/) 4.6 [(50)](https://www.softwareadvice.com/anti-spam/mcafee-security-for-email-servers-profile/reviews/) Pricing: Available upon request Free trial Free version Pricing: Available upon request Free trial Free version ### Features Comparison 33% Unique Features for McAfee Security for Email Servers - Threat Response 67% Shared Features with Microsoft Defender for Office 365 - Email Filtering - Threat Protection ### Integrations Comparison 0% Unique Integrations for McAfee Security for Email Servers - No unique integrations 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See McAfee Security for Email Servers Screenshots [### Encyro](https://www.softwareadvice.com/electronic-signature/encyro-profile/) 5.0 [(48)](https://www.softwareadvice.com/electronic-signature/encyro-profile/reviews/) Starting Price: $14.99 per month Free trial Free version Starting Price: $14.99 per month Free trial Free version ### Features Comparison 94% Unique Features for Encyro - Access Controls/Permissions - Alerts/Notifications - Audit Trail See All 6% Shared Features with Microsoft Defender for Office 365 - Email Attachment Protection - Threat Protection ### Integrations Comparison 100% Unique Integrations for Encyro - Gmail - Microsoft Outlook 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Encyro Screenshots [### Barracuda Impersonation Protection](https://www.softwareadvice.com/anti-spam/barracuda-sentinel-profile/) 4.6 [(11)](https://www.softwareadvice.com/anti-spam/barracuda-sentinel-profile/#reviews) Pricing: Available upon request Free trial Free version Pricing: Available upon request Free trial Free version ### Features Comparison 60% Unique Features for Barracuda Impersonation Protection - Fraud Detection - Reporting/Analytics - Threat Response 40% Shared Features with Microsoft Defender for Office 365 - Email Filtering - Threat Protection ### Integrations Comparison 0% Unique Integrations for Barracuda Impersonation Protection - No unique integrations 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Barracuda Impersonation Protection Screenshots [### Abnormal AI](https://www.softwareadvice.com/anti-spam/abnormal-security-profile/) 5.0 [(2)](https://www.softwareadvice.com/anti-spam/abnormal-security-profile/#reviews) Pricing: Available upon request Free trial Free version Pricing: Available upon request Free trial Free version ### Features Comparison 56% Unique Features for Abnormal AI - Anomaly/Malware Detection - Anti Virus - Monitoring See All 44% Shared Features with Microsoft Defender for Office 365 - Alerts/Escalation - Email Attachment Protection - Phishing Protection See All ### Integrations Comparison 0% Unique Integrations for Abnormal AI - No unique integrations 0% Shared Integrations with Microsoft Defender for Office 365 - No shared integrations See Abnormal AI Screenshots ## Popular Microsoft Defender for Office 365 Comparisons [Hoxhunt vs Microsoft Defender for Office 365](https://www.softwareadvice.com/email-security/hoxhunt-profile/vs/microsoft-defender-for-office-365/)[SpamTitan vs Microsoft Defender for Office 365](https://www.softwareadvice.com/anti-spam/microsoft-defender-for-office-365-profile/vs/spamtitan/)[Proton Mail vs Microsoft Defender for Office 365](https://www.softwareadvice.com/anti-spam/microsoft-defender-for-office-365-profile/vs/protonmail/)[ESET Endpoint Security vs Microsoft Defender for Office 365](https://www.softwareadvice.com/security/eset-endpoint-security-profile/vs/microsoft-defender-for-office-365/)