# MasterControl Quality Excellence vs Pico MES - 2026 Comparison - Software Advice > MasterControl Quality Excellence vs Pico MES - See how these products stack up against each other with real user reviews, product feature comparisons and screenshots. Find out which one is best for your organization. Source: https://www.softwareadvice.com/manufacturing/mastercontrol-profile/vs/pico-mes --- [Home](https://www.softwareadvice.com/) / [Manufacturing Execution Software](https://www.softwareadvice.com/manufacturing/execution-systems-comparison/) / MasterControl Quality Excellence vs Pico MES Software Advice offers objective insights based on verified user reviews and independent product and market research. When our advisors match you to a software provider, we may earn a referral fee. Updated May 24, 2026 # MasterControl Quality Excellence vs. Pico MES: 2026 Comparison Skip hours of research. Get your top 5 matches from an expert in 15 minutes, 100% free. Free Expert Guidance Real Human Advice 1M + Businesses Helped Updated May 24, 2026 # MasterControl Quality Excellence vs. Pico MES: 2026 Comparison Skip hours of research. Get your top 5 matches from an expert in 15 minutes, 100% free. Free Expert Guidance Real Human Advice 1M + Businesses Helped Product comparison Compare up to 3 products side-by-side + Add product [](https://www.softwareadvice.com/manufacturing/mastercontrol-profile/) [MasterControl Quality Excellence](https://www.softwareadvice.com/manufacturing/mastercontrol-profile/) 4.5 [(534)](https://www.softwareadvice.com/manufacturing/mastercontrol-profile/reviews/) Starting Price $25000.00per year Free trial Free version Pros: - Customer Support - Training and Learning Curve Cons: - Reporting - Ease of Use Who uses MasterControl Quality Excellence Based on 534 reviews - Popular among: Enterprise organizations - Most common industry: Health & Medicine (83%) - Top use case: Quality Management (63%) 68% of users recommend this product [](https://www.softwareadvice.com/manufacturing/pico-mes-profile/) [Pico MES](https://www.softwareadvice.com/manufacturing/pico-mes-profile/) 4.7 [(26)](https://www.softwareadvice.com/manufacturing/pico-mes-profile/reviews/) Starting Price $100.00per month Free trial Free version Pros: Not enough reviews Cons: Not enough reviews Who uses Pico MES Based on 26 reviews - Top use case: Manufacturing Execution (100%) 100% of users recommend this product [](https://www.softwareadvice.com/manufacturing/mastercontrol-profile/) MasterControl Quality Excellence 4.5 [(534)](https://www.softwareadvice.com/manufacturing/mastercontrol-profile/reviews/) [](https://www.softwareadvice.com/manufacturing/pico-mes-profile/) Pico MES 4.7 [(26)](https://www.softwareadvice.com/manufacturing/pico-mes-profile/reviews/) + Add product Add product ## User satisfaction * * * 4.5 Based on 534 reviews Ease of use 4.1 Value for money 4.2 Customer support 4.5 Functionality 4.2 4.7 Based on 26 reviews Ease of use 4.7 Value for money 4.9 Customer support 4.8 Functionality 4.6 ## User interface * * * ## Key features Features selected based on 560 reviews from Manufacturing Execution * * * Access Controls/Permissions 4.4 Archiving & Retention 4.6 Collaboration Tools 4.2 Compliance Tracking 4.0 Document Generation 4.4 Electronic Signature 4.8 Access Controls/Permissions N/A Archiving & Retention N/A Collaboration Tools N/A Compliance Tracking N/A Document Generation N/A Electronic Signature N/A ### Wondering if these products fit your needs? Skip the manual research. Talk to a real advisor like Lexi to get a 100% free, personalized shortlist in 15 minutes. LexiAdvisor for 8 years ### Wondering if these products fit your needs? Skip the manual research. Talk to a real advisor like Lexi to get a 100% free, personalized shortlist in 15 minutes. LexiAdvisor for 8 years ## Integrations * * * [ Microsoft WordNot enough reviews ](https://www.softwareadvice.com/cms/microsoft-word-profile/)[ Microsoft PowerPointNot enough reviews ](https://www.softwareadvice.com/presentation/microsoft-powerpoint-profile/)[ Microsoft ExcelNot enough reviews ](https://www.softwareadvice.com/productivity/microsoft-excel-profile/) [ JiraNot enough reviews ](https://www.softwareadvice.com/project-management/atlassian-jira-profile/)[ Infor VISUALNot enough reviews ](https://www.softwareadvice.com/manufacturing/infor-visual-profile/)[ Odoo Not enough reviews ](https://www.softwareadvice.com/crm/odoo-profile/) ## Reviews * * * Marco B.IT Senior Application SpecialistBiotechnology, 1001-5000 employees "I especially appreciate the ready‑to‑use digital forms, which are already designed around industry‑standard processes and allow teams to start working immediately without lengthy configuration." Feb 16, 2026 Simone B.Quality compliance specialistPharmaceuticals, 1001-5000 employees "Certain configurations and workflow customizations require significant administrative support and can become time-consuming." May 20, 2026 PC Paul C.InstructorEducation Management, 11-50 employees "Provided training and webinars to show my students what a 'Good Work Instruction' looks like." Sep 28, 2025 BM Ben M.Manufacturing EngineerDesign, 201-500 employees "For the operator, there is no search function to find instructions on a page. If a station has a lot of things that could be built there, and we aren't using work orders to drive, then it becomes difficult to find one instruction among 99 others." Jun 14, 2024 ## Customer support * * * Email/Help Desk FAQs/Forum Knowledge Base Phone Support 24/7 Chat Email/Help Desk FAQs/Forum Knowledge Base Phone Support 24/7 Chat ## Training options * * * In Person Live Online Webinars Documentation Videos In Person Live Online Webinars Documentation Videos ## Popular Comparisons * * * [Isolocity vs MasterControl Quality Excellence](https://www.softwareadvice.com/manufacturing/isolocity-profile/vs/mastercontrol/)[KAWAK vs MasterControl Quality Excellence](https://www.softwareadvice.com/manufacturing/kawak-profile/vs/mastercontrol/)[MasterControl Manufacturing Excellence vs Pico MES](https://www.softwareadvice.com/manufacturing/mastercontrol-manufacturing-excellence-profile/vs/pico-mes/)[Redzone vs Pico MES](https://www.softwareadvice.com/manufacturing/pico-mes-profile/vs/redzone-productivity/)