---
title: "RealTime-CTMS Reviews, Pros and Cons - 2026 Software Advice"
description: "Reviews of RealTime-CTMS. Learn how real users rate this software's ease-of-use, functionality, overall quality and customer support. Talk to our advisors to see if RealTime-CTMS is a good fit for you!"
source_url: "https://www.softwareadvice.com/clinical-trial-management/realtime-ctms-profile/reviews/"
page_type: "reviews"
language: "en"
---

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RealTime-CTMS Reviews

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# RealTime-CTMS User Reviews

## Reviews summary

- Overall rating: 4.9/5
- Total reviews: 68

### Secondary ratings

- Ease of use: 4.7/5
- Customer support: 4.9/5
- Value for money: 4.8/5
- Functionality: 4.7/5

### Rating distribution

- 5 stars: 58 reviews (85%)
- 4 stars: 10 reviews (15%)
- 3 stars: 0 reviews (0%)
- 2 stars: 0 reviews (0%)
- 1 star: 0 reviews (0%)

### Most mentioned pros

- The accuracy and regulatory compliance offered by RealTime CTMS are paramount in clinical research.3.
- With a user-friendly interface and a commitment to customer satisfaction, it's a top choice for clinical research professionals seeking efficiency and ease of use.
- You can build the budget and as visits are completed easily see the funds due and send invoices if needed. When we have concerns we have voiced them and the team listens and finds solutions or upgrades to make the system more user friendly.

### Most mentioned cons

- Sometimes the Images don't load, records are not not readable but over all this is just a small issue.
- The labeling of different sections seems rather obtuse (and I think, for example, it's strange to track user accounts for external providers/visiting Monitors in a completely separate location from user accounts for site staff - shouldn't all user accounts be in one place?).
- It is not very easy to post a check that is paid with many line items and payment amounts that need to be adjusted to match the sponsor payment. When emailing invoice to sponsor, there is no mechanism to ensure email was received such as a reach receipt by Sponsor.

## RealTime-CTMS customer reviews

Showing reviews 1-25 of 68 (page 1).

### Specific to your site

- Overall rating: 5/5
- Reviewer: Casey R.
- Verified reviewer: Yes
- Industry: Hospital & Health Care
- Company size: 11-50 employees
- Product usage: Used daily for less than 6 months
- Reviewed: December 2019
- Review source details: This review was submitted organically. No incentive was offered

I've used other CTMS software companies and RealTime is leaps and bounds above. Everything I wished the others had, RT does. It saves me so much time on the reports, logs, stats that I was previously maintaining and calculating manually. It is set up custom to your site. The training is scheduled with your staffs availability and is very efficient, precise, effective and clear. I can't say enough.

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

The time it saves on reports and stats. The ease of use. The TEXT and PAY features. The ease of use. The time saving it provides.

#### Cons

So far, I have no negative experiences. I have no cons to report.

#### Reasons for switching to RealTime-CTMS

IBM is discontinuing its CTMS support

---

### CTMS Every Day User - Easy to Navigator and All-Around System for Clinical Research

- Overall rating: 5/5
- Reviewer: Keihanna D.
- Verified reviewer: Yes
- Industry: Research
- Company size: 11-50 employees
- Product usage: Used daily for more than 2 years
- Reviewed: December 2021
- Review source details: This review was submitted organically. No incentive was offered

RealTime-CTMS is the only clinical trial management system our company utilizes. It is an all-around system that can navigator all aspects of clinical trials from patient visits, electronic data capture, subject stipends, to electronic regulatory document creation and storage.

#### Ratings breakdown

- Ease of use: 5/5
- Customer support: 5/5
- Functionality: 4/5

#### Pros

I like that we can complete patient visits from start to finish within one system as well as maintain an electronic Investigator Site File. CTMS makes it easier to reduce our company's carbon footprint by functioning well as an electronic system.

#### Cons

eSource is a wonderful function, however, I believe that are a lot of ways it can improve. With some improvement, eSource can be much more user friendly and decrease the time it takes to create an eSource template to mimic eCRF guidelines.

---

### RealTime-CTMS has directly contributed to our site's success!

- Overall rating: 5/5
- Reviewer: Emmet F.
- Verified reviewer: Yes
- Industry: Pharmaceuticals
- Company size: 201-500 employees
- Product usage: Used daily for less than 2 years
- Reviewed: May 2019
- Review source details: This review was submitted organically. No incentive was offered

Endeavor Clinical Trials is capitalizing on the detailed reporting features built-in with RealTime to help us keep accurate metrics on recruitment and marketing.

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

RealTime-CTMS is a user-friendly clinical trials management software that allows us to process potential candidates for studies from recruitment to completion! As the manager of recruitment, I am particularly excited about the API integration with our ad agency's digital advertising campaigns. If a potential patient clicks on a digital ad, our database is populated with the data from the patient in the specific study! It makes recruiting a breeze.

#### Cons

Sometimes the server can be a bit sluggish.

---

### CTMS, eDocs and eSource all in one package

- Overall rating: 4/5
- Reviewer: Kristina C.
- Verified reviewer: Yes
- Industry: Hospital & Health Care
- Company size: 201-500 employees
- Product usage: Used daily for less than 2 years
- Reviewed: December 2021
- Review source details: This review was submitted organically. No incentive was offered

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 4/5
- Functionality: 4/5

#### Pros

I like that everything is integrated in one place and it is easy to toggle between each side. Quality checks are easy to be completed because you can toggle from one place to another. When you load a new consent in eDocs it can automatically show and be tracked in the source and a log is made. I love the new electronic delegation log which prevents us from having to go to each person and get signatures. Once you put a patient into the CTMS you can easily attach that patient to a study and follow the patient throughout the process. You can build the budget and as visits are completed easily see the funds due and send invoices if needed. When we have concerns we have voiced them and the team listens and finds solutions or upgrades to make the system more user friendly.

#### Cons

If the internet goes out there is a problem. I wish there was a way to work offline when that happens. It doesn't happen often but when it does we have to get creative and use hot spots to continue to work.

#### Reasons for choosing RealTime-CTMS

Because it had everything in one neat integrated system.

---

### Each year they impress us more

- Overall rating: 5/5
- Reviewer: Fabian S.
- Verified reviewer: Yes
- Industry: Hospital & Health Care
- Company size: 11-50 employees
- Product usage: Used daily for more than 2 years
- Reviewed: February 2021
- Review source details: This review was submitted organically. No incentive was offered

Form day one it has been WONDERFUL. I enjoy the progress the company continues to make, which in turn benefits my research site, and the costs keep low. Thanks to the [SENSITIVE CONTENT HIDDEN] I have always felt that this leadership always takes into account the inform form sites in order to continue to improve the system. Having the direct line of communication to these two leaders, ensures that RealTime values our input and takes the time to work closely with its clients regardless of our company size.

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

The system is very user friendly and intuitive. I like the way the system has features in place where the study coordinators must complete sections before completing a visit, as this helps speed up the QC process for proper billing to our customers. The system does EVERYTHING we need from patient visits and Text reminders to invoice and payments to patients. The new customized reloadable cards that we give our patients are a wonderful addition and has saved us lots of time and money, plus take us to a new level of professionalism. providers, and support organizations also like the way we can provide a breakdown of payment to them. This one stop system keeps our research site moving smoothly.

#### Cons

There is a learning curve to integrate eSource, but they have a good help desk to teach you.

#### Reasons for choosing RealTime-CTMS

Cost, ease of use, and easy access to customer service.

---

### RealTime-CTMS Review

- Overall rating: 5/5
- Reviewer: Maria Paula Z.
- Verified reviewer: Yes
- Industry: Research
- Company size: 51-200 employees
- Product usage: Used daily for less than 2 years
- Reviewed: April 2024
- Review source details: This review was submitted organically. No incentive was offered

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

Real Time-CTMS offers a set of features that help clinical trial management. I also love the training program that covers every user's needs, and the customer service deserves a 5-star rating!

#### Cons

I wish there could be a way to import study visits. It would be such a time saver and minimize the risk of errors during data entry.

---

### Real Time

- Overall rating: 5/5
- Reviewer: Tim D.
- Verified reviewer: Yes
- Industry: Research
- Company size: 51-200 employees
- Product usage: Used daily for less than 2 years
- Reviewed: April 2023
- Review source details: This review was submitted organically. No incentive was offered

I thoroughly enjoy the software. It’s very helpful for our CRO

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

I enjoy the university. It’s great to always have that resources readily available

#### Cons

It’s so in-depth that it can seem daunting at times

---

### Cool Software that is always improving

- Overall rating: 5/5
- Reviewer: Brent N.
- Verified reviewer: Yes
- Industry: Medical Practice
- Company size: 2-10 employees
- Product usage: Used daily for less than 12 months
- Reviewed: February 2019
- Review source details: This review was submitted organically. No incentive was offered

Great way to implement a paperless trial site without using disparate systems. Awesome support and always improving features.

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

Support is friendly and quick to respond. Improvements are implemented on a regular basis and suggestions are taken seriously. The product is always evolving. Training is excellent. Cost of the product is very competitive and allows you to scale without taking on too much risk. Product features are progressive for the industry such as offering eSOURCE. The system is pretty easy to learn overall. The ability to purchase different pieces of the system a la carte is very nice and integration between the different pieces is reasonably good, though some future improvements would really make it stand out. Overall, RealTime is a fantastic company to work with and they have a great product.

#### Cons

Navigating on a web-based platform can be a little slower than a desktop install at times, even on a quick connection, but I would say the convenience of connecting outweighs the downside. The phone app is still a work in progress but is a bit limited at this point compared to the web version. Some features are buried in the menus and not the most intuitive or efficient to navigate to, but overall the system is very easy to use.

---

### eSource/eReg and so much more!

- Overall rating: 5/5
- Reviewer: Carmen B.
- Verified reviewer: Yes
- Industry: Research
- Company size: 11-50 employees
- Product usage: Used daily for less than 2 years
- Reviewed: December 2021
- Review source details: This review was submitted organically. No incentive was offered

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

We were looking for an electronic software program for our source and regulatory and decided on RealTime after our initial demo and meeting. It is obvious on all levels that the product has been designed by people that have worked in the clinical trial arena! We are just over a year into using RT and it has exceeded our needs. While the eSource side is less mature than the eReg it continues to develop and customer service readily takes suggestions with most ideas already on their roadmap. We continue to learn what it has to offer and have just begun looking into the text options. We also are interested in switching our CTMS in the future. I can not say enough about their support team, 5 stars all the way around!

#### Cons

The only thing I could mention is the learning curve upfront, but this would be with any new product and its implementation.

---

### How did we even function before RealTime-CTMS??

- Overall rating: 5/5
- Reviewer: Megan M.
- Verified reviewer: Yes
- Industry: Research
- Company size: 11-50 employees
- Product usage: Used daily for less than 2 years
- Reviewed: February 2019
- Review source details: This review was submitted organically. No incentive was offered

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

RealTime-CTMS makes it possible to complete tasks quickly. Having used other systems in the past, it was daunting to complete the most basic tasks such as adding a new patient and scheduling an appointment. Our biggest complaint with other systems was it took "too many clicks" to get these things done. This is not the case with RealTime-CTMS. This was clearly created by people who know about clinical trial ops. Everything we do on a daily basis is present in this system and is very intuitive and user friendly. The on-boarding training is excellent and site-specific. They even record it so that you can provide it to new staff.

#### Cons

There is nothing that I don't like but I do have a few things on my wish-list such as Outlook integration and allowing a user preference to show times in AM/PM format. We want to utilize the RealTime-Text feature but are concerned that many patients would get confused with the military time format.

---

### Valuable Software Package

- Overall rating: 5/5
- Reviewer: Miguel D.
- Verified reviewer: Yes
- Industry: Research
- Company size: 51-200 employees
- Product usage: Used daily for more than 2 years
- Reviewed: November 2020
- Review source details: This review was submitted organically. No incentive was offered

The customer service is exceptional. There is a learning curve but there is sufficient training and site support to help the system administrator get acclimated to the system.

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

The eSource, eDocs and invoicing features are intuitive, functional and help streamline our processes.

#### Cons

Would like to see an updated accounting dashboard.

#### Reasons for choosing RealTime-CTMS

RealTime-CTMS provided more features.

#### Reasons for switching to RealTime-CTMS

Our company outgrew the software.

---

### Great CTMS, even greater Service

- Overall rating: 5/5
- Reviewer: Markus L.
- Verified reviewer: Yes
- Industry: Research
- Company size: 2-10 employees
- Product usage: Used daily for less than 12 months
- Reviewed: May 2019
- Review source details: This review was submitted organically. No incentive was offered

#### Ratings breakdown

- Ease of use: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

Their customer support team is one of the best I've encountered. They are consistently friendly and knowledgeable. The training is high quality and thorough. The program itself is easy to use and the reporting is excellent. There are many tools that cut down the work of a very complicated business. Overall this is a great product. Most importantly, they continually request feedback and look for opportunities to improve.

#### Cons

There are a few features that could be added to improve quality of life. Fortunately I've been informed that some of these are already in the works such as improved audit logs in the accounting area. I'd also like some more flexibility in the information that is included/excluded on invoices or simply the ability to edit them after creation.

---

### ERG Realtime Implementation and Usage

- Overall rating: 5/5
- Reviewer: David H.
- Verified reviewer: Yes
- Industry: Hospital & Health Care
- Company size: 501-1000 employees
- Product usage: Used daily for less than 2 years
- Reviewed: April 2021
- Review source details: This review was submitted organically. No incentive was offered

Overall experience is exceptionally good. Wonderful team to work with. They are open to our multiple product enhancement suggestions, and I value them as a partner. Great customer support. Their technology roadmap is exciting, and I look forward to our future together.

#### Ratings breakdown

- Ease of use: 4/5
- Value for money: 5/5
- Customer support: 4/5
- Functionality: 4/5

#### Pros

Recruitment features and reporting capabilities are excellent

#### Cons

Accounting module needs to be improved. eConsent function would be a great addition

---

### Wouldn't do clinical research without a CTMS

- Overall rating: 5/5
- Reviewer: Justin B.
- Verified reviewer: Yes
- Industry: Research
- Company size: 2-10 employees
- Product usage: Used daily for more than 2 years
- Reviewed: March 2019
- Review source details: This review was submitted organically. No incentive was offered

Excellent. Realize that taking full advantage of the CTMS requires diligent management know-how in order to effectively create the process for maximizing the CTMS's benefit.

#### Ratings breakdown

- Ease of use: 4/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

This makes tracking our incoming payments SO much easier. Honestly, the more areas that I can get the CTMS implemented, the better the information I have to manage the business.

#### Cons

It does take a while for new features to be implemented.

---

### Excellent Customer Service

- Overall rating: 5/5
- Reviewer: Danielle H.
- Verified reviewer: Yes
- Industry: Research
- Company size: 11-50 employees
- Product usage: Used daily for less than 12 months
- Reviewed: December 2021
- Review source details: This review was submitted organically. No incentive was offered

I enjoy working with this system. There are some features that go unused or under-utilized, but hopefully my employer will upgrade that in the future.

#### Ratings breakdown

- Ease of use: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

This software was easy to learn with informative instructional training videos. If I have a question or suggestion, customer service always responds timely and makes me feel important.

#### Cons

I'd like the reports to be more personalized. I look forward to that possibility in the future.

---

### Realtime CTMS

- Overall rating: 5/5
- Reviewer: Dominic B.
- Verified reviewer: Yes
- Industry: Research
- Company size: 11-50 employees
- Product usage: Used daily for more than 2 years
- Reviewed: April 2019
- Review source details: This review was submitted organically. No incentive was offered

This software has quickly become an essential part of our busy research site operations. A very contemporary and cost effective tool for systematic business management improvement

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

Multiple efficiencies vs older practices

#### Cons

US- based so communications difficult from time to time

---

### all

- Overall rating: 5/5
- Reviewer: Robert L.
- Verified reviewer: Yes
- Industry: Research
- Company size: 2-10 employees
- Product usage: Used daily for less than 12 months
- Reviewed: June 2021
- Review source details: This review was submitted organically. No incentive was offered

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Pros

I believe that this software has all the tools that we need to conduct our clinical trials without any stress, I love everything about this software/

#### Cons

There is nothing that I don't like about the software

#### Reasons for choosing RealTime-CTMS

Because it is an amazing software that help to make you work flow a lot easy.

---

### Great customer support

- Overall rating: 5/5
- Reviewer: Gustavo R.
- Verified reviewer: Yes
- Industry: Research
- Company size: 1001-5000 employees
- Product usage: Used daily for less than 12 months
- Reviewed: November 2021
- Review source details: This review was submitted organically. No incentive was offered

Very Good

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 4/5

#### Pros

It's user friendly and customer service is always great

#### Cons

None at this time but working with the team at Real-Time for better experience

---

### eSource functionality.

- Overall rating: 5/5
- Reviewer: Dalan A.
- Verified reviewer: Yes
- Industry: Research
- Company size: 2-10 employees
- Product usage: Used daily for less than 12 months
- Reviewed: October 2019
- Review source details: This review was submitted organically. No incentive was offered

#### Ratings breakdown

- Ease of use: 4/5
- Customer support: 5/5
- Functionality: 3/5

#### Pros

The ease of creating source (i.e. drag and drop).

#### Cons

Sometimes more complicated than instinctive. Navigating between features can be confusing without constant use or repetition.

---

### So happy to use RealTime as my CTMS

- Overall rating: 5/5
- Reviewer: Ken A.
- Verified reviewer: Yes
- Product usage: Used unspecified for unspecified
- Reviewed: September 2016
- Review source details: This review was submitted organically. No incentive was offered

1. System is user friendly to the point of being intuitive 2. Service is first rate ... accessible and knowledgeable ... and provides solutions the first try 3. RT is clearly run by folks with research site level experience rather than IT folks 4. RT is clearly interested in what their customers think ... and this survey is NOT the first example of this ... they listen and respond 5. RT helps us populate studies ... the system works!

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 5/5

#### Vendor response

Ken, we are very happy that the system is working great for you. Thank you for being a RealTime customer!

Replied February 2017

---

### RealTime staff have been most helpful

- Overall rating: 5/5
- Reviewer: Kim N.
- Industry: Research
- Company size: 2-10 employees
- Product usage: Used daily for less than 6 months
- Reviewed: April 2018
- Review source details: This review was submitted organically. No incentive was offered

#### Ratings breakdown

- Ease of use: 3/5
- Value for money: 4/5
- Customer support: 5/5
- Functionality: 4/5

#### Pros

software appears to have a lot of functionality that will help my site be more financially organized

#### Cons

software if overwhelming at first. hard to learn all it has to offer. wish the training sessions were more "hands on"

---

### Excellent CTMS

- Overall rating: 5/5
- Reviewer: Juan C.
- Product usage: Used unspecified for unspecified
- Reviewed: December 2016
- Review source details: This reviewer was invited by us to submit an honest review and offered a nominal incentive as a thank you.

Great value for the price. Easy to use and helps us keep upcoming and ongoing under control. Budgeting and visit payment control have increased our revenue as our visits don't drop through the cracks.

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 4/5

#### Vendor response

Hi Juan. Thank you for the nice review. We're happy that RealTime has helped increase revenue at your site.

Replied March 2017

---

### This CTMS covers all the bases, gives you solid tracking capabilities, and won't take forever to get the hang of.

- Overall rating: 4/5
- Reviewer: Leslie H.
- Verified reviewer: Yes
- Industry: Financial Services
- Company size: 2-10 employees
- Product usage: Used weekly for less than 6 months
- Reviewed: August 2026
- Review source details: This review was submitted organically. No incentive was offered

Honestly, my experience with RealTime-CTMS has been pretty good overall. It gives you one central place to manage recruitment, participant visits, study activities, financials, and reporting — which means we're not juggling a dozen spreadsheets anymore. It's much easier to get a quick sense of where each study stands. For day-to-day stuff, it's pretty intuitive. Scheduling visits, pulling up participant info, tracking recruitment — those all work smoothly. That said, the more advanced stuff like setting up a new study, digging into accounting reports, managing permissions, or handling integrations definitely takes some extra training. Once you've got everything configured the way you want, it does end up saving a lot of administrative time. Feature-wise, this platform has a lot going for it, especially for a research site. The appointment reminders, visit tracking, automatic target-date calculations, recruitment tools, financial reports, and document storage are all genuinely useful. I also like that you can attach files directly to a study and share them easily. But keep in mind, it's not really built to be a general file-management tool — that's just not its main strength. Exporting and file conversion work fine for standard reports and day-to-day operational data. But if you need something for an external presentation, be prepared to do some manual formatting afterward. More flexibility with report layouts and export options would definitely be a nice upgrade. Customer support has been decent for routine questions — they're responsive and helpful. But when you get into trickier configuration problems or financial glitches, you might need to go back and forth a bit. I've also hit a few bugs here and there, though nothing that's ever stopped me from using the system for long. For a busy research site that uses the recruitment, scheduling, financial, and reporting features daily, the cost is pretty reasonable. But if you're a smaller organization with only a handful of studies, the price tag and the time it takes to set everything up might be a tougher sell. All in all, RealTime-CTMS is a solid, comprehensive system. It just has a learning curve, occasional quirks, and some reporting limitations that keep it from being perfect.

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 4/5
- Functionality: 4/5

#### Pros

RealTime-CTMS has made a real difference in how we run clinical research. It pulls together all the key pieces — enrolling participants, scheduling visits, keeping track of studies, sending appointment reminders, and managing the financial side of things. The calendar with automatic visit-window calculations is a big help for staying on top of deadlines, and it's definitely reduced scheduling errors. I also appreciate the recruitment tracking feature, which gives a clear view of where prospective participants are in screening. But what I value most is how it links operational and financial data, giving the team real insight into study performance.

#### Cons

There’s no shortage of features here, but that definitely comes with a learning curve when you're just getting started. Some screens feel a bit cluttered, and a few workflows take more clicks than you'd expect. Getting studies, financial rules, reports, and user permissions configured requires time and careful attention. I've also run into the occasional bug or hiccup—mostly with loading times, notifications, and data refreshing. The reports and exported files are useful, though the layout and customization options could be a lot more flexible. And for smaller research sites, the price tag might be tough to justify.

---

### Great Value and Functionality, Hoping Support Bounces Back

- Overall rating: 4/5
- Reviewer: Ricardo C.
- Verified reviewer: Yes
- Industry: Pharmaceuticals
- Company size: 51-200 employees
- Product usage: Used daily for more than 2 years
- Reviewed: August 2026
- Review source details: This review was submitted organically. No incentive was offered

My personal experience with RealTime-CTMS since 2017 has been overwhelmingly positive. The platform offers a complete, user-friendly, and cost-effective solution built specifically around the daily operational and financial needs of a clinical research site. While we have encountered a temporary increase in system bugs and slower support ticket resolution times in recent months, upper management stepped in to help address our critical issues, and we have been informed that structural changes are currently being made to improve support responsiveness. Overall, we view these recent challenges as short-term growing pains, and we remain confident in our continued partnership with RealTime given their strong track record and robust system capabilities.

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 4/5
- Functionality: 5/5

#### Pros

RealTime-CTMS is an exceptionally user-friendly platform clearly built from the clinical research site perspective. Having used the system since 2017, I consider it a great value for the money, offering a robust feature set that easily rivals any major competitor in the industry. It comprehensively covers all operational and financial aspects of running a site through its various integrated modules. The platform excels at managing recruitment efforts and tracking enrollment via its CRM capabilities, streamlines study visit logistics through intuitive study templates and clear visit tracking, and provides seamless electronic source data capture through eSOURCE along with clean Investigator Site File organization in eDOCS. Overall, it delivers a complete, site-centric solution that effectively powers daily operations and financial management.

#### Cons

Recently, our team has experienced an increase in system bugs alongside a decline in support responsiveness, with open tickets taking much longer to resolve than in the past. Critical issues, such as inaccurate financial report data and an ongoing inability to merge duplicate subject profiles, remained open for weeks, with the duplicate profile issue still unresolved. While direct phone support was previously easy to access, resolving recent issues required escalation through upper management. That said, company leadership has communicated that structural changes are underway to address support timeliness, so these recent setbacks appear to be growing pains rather than a permanent shift.

#### Reasons for choosing RealTime-CTMS

We had a less than ideal experience with CRIO during a study where the sponsor provided the access.

---

### RealTim-CTMS Review

- Overall rating: 5/5
- Reviewer: Diana T.
- Verified reviewer: Yes
- Industry: Medical Practice
- Company size: 11-50 employees
- Product usage: Used weekly for less than 12 months
- Reviewed: May 2026
- Review source details: This review was submitted organically. No incentive was offered

My experience with RealTime-CTMS is that the information is real time and is available to you quickly on a real time basis, very helpful when is dealing with patient care on a day to day basis.

#### Ratings breakdown

- Ease of use: 5/5
- Value for money: 5/5
- Customer support: 5/5
- Functionality: 4/5

#### Pros

We like to use RealTime CTMS to view patient records and images for patients interventions and surgical options.

#### Cons

Sometimes the Images don't load, records are not not readable but over all this is just a small issue. That can be overcome.

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RealTime-CTMS Reviews, Pros and Cons - 2026 Software Advice