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Fishbowl is the #1 manufacturing and warehouse inventory management software! Its powerful inventory control system gives your small or midsize business the exact tools needed to transform your inventory management and scale your ...Read more about Fishbowl

4.2 (896 reviews)

66 recommendations


DELMIAworks (formerly IQMS) ERP is developed specifically for SMB and large discrete and batch process manufacturers in the aerospace, medical device, automotive, food and beverage, consumer products, plastics, packaging, and elec...Read more about DELMIAworks

4.1 (288 reviews)

17 recommendations

R4 Enterprise

Royal 4 Enterprise is an integrated enterprise resource planning (ERP) solution with built-in modules for distribution, manufacturing, planning, inventory management, reporting and company financials. It serves midsize to large en...Read more about R4 Enterprise

4.5 (4 reviews)

12 recommendations


Vicinity Software is a cloud-based or on-premise solution designed for process manufacturers with a specific focus on food & beverage (VicinityFood), chemical (VicinityChem) and breweries (VicinityBrew). Features include MRP, cent...Read more about Vicinity

4.3 (4 reviews)

11 recommendations

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SafetyChain's digital plant management platform gives process manufacturers the flexibility to rapidly address urgent challenges while offering scalability to expand and drive long-term value. • Gain visibility and control of qua...Read more about SafetyChain

4.6 (58 reviews)

8 recommendations


Mar-Kov provides the best manufacturing software for batch and process manufacturers in the market. Companies turn to Mar-Kov when: • Their business outgrows excel sheets and are looking to manage their growing production. • T...Read more about Mar-Kov

5.0 (6 reviews)

5 recommendations

Deskera MRP

Deskera enables fast growing businesses to operate more efficiently by providing them with an integrated platform that connects manufacturing, accounting, erp, inventory and warehouse management, order fulfillment, procurement, sa...Read more about Deskera MRP

3.7 (3 reviews)

5 recommendations

Datacor ERP

Datacor ERP (formerly Chempax) is an integrated enterprise resource planning (ERP) and customer relationship management (CRM) application designed specifically for chemical process manufacturers and distributors. The solution can ...Read more about Datacor ERP

4.2 (57 reviews)

4 recommendations

BatchMaster ERP

BatchMaster Software offers process manufacturing software solutions for the food, chemical, nutraceutical and pharmaceutical industries. Users can run the manufacturing application with QuickBooks, Sage 100&300, Microsoft Dynamic...Read more about BatchMaster ERP

4.7 (6 reviews)

4 recommendations

Acumatica Cloud ERP

Acumatica Cloud ERP provides the best business management solution for transforming your company to thrive in the new digital economy. Through leading-edge technology, best-in-class business functionality, and customer-friendly ...Read more about Acumatica Cloud ERP

4.3 (125 reviews)

3 recommendations


Online Computing designs and develops a proprietary ERP software called MasterTools. MasterTools combines all aspects of production planning, project management, shop floor control, inventory control, e-commerce, and financial ana...Read more about MasterTools

No reviews yet

2 recommendations


SAP S/4HANA Cloud is a cloud-based and on-premise enterprise resource planning (ERP) solution. It is suitable for small, midsize and large businesses in industries such as automotive, engineering, construction, mining, research an...Read more about SAP S/4HANA Cloud

4.4 (334 reviews)

1 recommendations


MRPeasy is a versatile cloud-based ERP system for small and scaling companies (perfect for up to 200 employees). The software offers a complete ERP solution with robust production planning and inventory management functionalities ...Read more about MRPeasy

4.5 (103 reviews)

1 recommendations

QAD Adaptive ERP

QAD Adaptive ERP is a cloud-based solution for manufacturing businesses in the food and beverage, automotive, consumer products, industrial, life sciences, and high tech industries. It combines ERP, supply chain, finance, and cust...Read more about QAD Adaptive ERP

3.7 (19 reviews)

1 recommendations

AcctVantage ERP

AcctVantage ERP is an agile, pain-free ERP system built for distributors, manufacturers and online retailers. Get all of your departments on the same page. Built for growing small & mid-sized businesses with inventory looking t...Read more about AcctVantage ERP

4.7 (9 reviews)

1 recommendations

Katana Cloud Inventory

Katana's Cloud Inventory Platform gives you live insights into sales, purchasing, and production to maintain optimal inventory levels in real time. Easily manage incoming orders from all your sales channels and issue purchase orde...Read more about Katana Cloud Inventory

JD Edwards EnterpriseOne

Oracle JD Edwards EnterpriseOne is an enterprise resource planning software with primary features such as real estate management, human capital management, environmental health and safety and commodity trading. What is JD...Read more about JD Edwards EnterpriseOne

MasterControl Manufacturing Excellence

MasterControl Manufacturing Excellence is a cloud-based manufacturing execution software designed to assist businesses with automating processes related to product lifecycle management. Key features include document management, qu...Read more about MasterControl Manufacturing Excellence

Acctivate Inventory Management

Built for growing product-selling businesses using QuickBooks, Acctivate is a premium inventory management & multi-channel order fulfillment add-on that helps you focus on growth without operational limitations. Solve for QuickBo...Read more about Acctivate Inventory Management


About SYSPRO SYSPRO is an enterprise resource planning (ERP) solution that is industry-built and provides last-mile capabilities for manufacturing and distribution businesses. SYSPRO provides the solutions, processes, and tools to...Read more about SYSPRO

Buyers Guide

Last Updated: March 16, 2023

In this buyers guide, we'll cover:

What is Chemical Manufacturing Software?

Chemical manufacturing software is an inventory, resource, and order management program designed specifically for chemical manufacturers. The software will support the strict security, compliance, and sensitive material handling requirements in this industry.

Benefits of Chemical Manufacturing software

A chemical manufacturing software supports the business across the lifecycle of the products produced and sold. Here are 3 key business problems a chemical manufacturing system can help alleviate.

1. Compliance documentation

Not only are chemical manufacturers regulated, the regulating agencies vary depending on the chemicals produced. The ATF, DEA, FSIS, EPA or FDA may be involved. Most likely, more than one agency will require compliance documentation.

2. Inventory management

The ingredients or the finished products may be controlled substances. Inventory storage can be problematic with chemicals. Some have particular storage requirements regarding temperature or humidity. Others should not be stored in combination, like chlorine and ammonia. Many chemicals have a limited shelf life. Some chemicals have strict regulations concerning disposal. Even shipping is regulated in many cases. The inventory system should assist with all of these issues.

3. Order entry and fulfillment

If the chemicals are restricted, the order entry system must identify the customer securely. The required material safety data sheets (MSDSes) must be enclosed. The shipping labels must include any required warnings. The receiving system should mirror the order entry and fulfillment systems. The vendor should be securely identified. The vendor should issue an advance shipping notice (ASN). Any discrepancies should be identified by the system and sent to management so that the appropriate authorities are notified.

Common Features of Chemical Manufacturing Software

Chemical manufacturers should examine the following functions to meet their unique requirements:

Available to promise, Capable to promise

Available to promise (ATP) and capable to promise (CTP) are measures of manufacturing capacity. The system should calculate the ATP and CTP for any stock item, accounting for ingredients on hand and any work in process.

MSDS handling

OSHA requires that the MSDS for a product be delivered by the seller, but only for certain customers. The system should have a repository of all MSDSes. The fulfillment system, based on information from the CRM system, should identify (or produce) any required data sheets for packing.

Integration with ERP

If the chemical manufacturing facility is part of a larger operation, the manufacturing software must integrate with the parent software. It can either be a set of modules of an ERP system or or it can pass required transaction data.

Lot tracing and recall management

Each lot must be identified and tracked. The ingredients of each batch must be tied to their individual batch number as well.

Recall management

Recalls are initiated for two reasons. First, a problem in the process causes a product to become tainted or contaminated. Second, an ingredient is tainted or contaminated. In either case, the system needs to identify all of the affected batches and the customers that received those batches.

Hazard Analysis Critical Control Points (HACCP) compliance

The system should support reporting for Hazard Analysis Critical Control Points (HACCP) management, in accordance with HACCP Principle 7: “Establish record-keeping and documentation procedures.”

ATF compliance

If a chemical manufacturer makes explosives or any of the components used in explosives, it is subject to ATF oversight. The Safe Explosives Act, among others, details required compliance reporting, including reporting theft and loss.

FDA compliance

If a chemical manufacturer makes products that are used in the manufacturing of food or drugs, the compounds may be regulated by the FDA. The system should provide all compliance reporting and support the petitioning process. The system should maintain records in compliance with the Public Health Security and Bioterrorism Preparedness and Response Act of 2002.

Food Safety Inspection Service (FSIS) compliance

If the chemical manufacturer makes products for agricultural purposes, it may be subject to FSIS-specific sections of HACCP, sections 326.6(b) and 381.606(b). The system should maintain records as mandated under section 417.5.

DEA compliance

If the chemical manufacturer makes products or uses ingredients regulated under the Controlled Substances Act, it is subject to oversight from the DEA. The system should document compliance with the act and have access to a current database of controlled substances, regulated chemicals and analogues.

Environmental Protection Agency (EPA) compliance

If the chemical manufacturer makes or uses products listed under the Toxic Substance Control Act, the substance may be regulated by the EPA. The system should maintain all compliant records as well as preparing a pre-manufacture notice (PMN) before a new compound is created.

Recipe management and batch sizing

The system should include recipe management, including ingredient substitution and batch scaling. In some cases, ingredients are encoded to keep the recipes secret. Advanced systems can size batches to quantities of ingredients in stock.

Quality assurance

The system should support quality assurance (QA) testing. The protocols should be documented and implemented through the software. The QA system should randomly identify samples for testing and compare test results against norms. Advanced systems will feature dashboards that will alert management to problems with quality.

Code of Federal Regulations 21 Part 11 compliance

Strictly speaking, no software package can be 21 CFR Part 11 compliant because the rule stipulates administrative and procedural controls as well as technical implementation for electronic and hybrid record keeping. However, it can support 21 CFR Part 11 by completely implementing the technical requirements.

Current Good Manufacturing Practice (cGMP) compliance

cGMP compliance is required for many regulatory agencies at the state and federal levels as well as for insurance purposes. The system should produce required compliance reports.

Yield variances

The system should track actual yield versus expected yield for each batch. The system should report excessive variance based on user-defined thresholds and indicate if variances are so large that regulating agencies should be notified.

Packing & drumming

The inventory system must be able to value and price items in different container sizes. It must also identify or generate suitable labels for containers.

Inventory storage planning

Some chemicals require a specific storage environment. Some are dangerous to store in combination. The inventory system and receiving systems should notify any special requirements. Advanced systems will have three-dimensional models of the storage areas for products and ingredients and automatically check for potential storage issues.

Expiration tracking

Both chemical ingredients and chemical products can have limited shelf lives. The system needs to track expired and close-to-end-of-life inventory.


Many chemicals have restrictions on shipping either via USPS or common carrier. The system should identify any special requirements and produce appropriate shipping labels.