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Updated October 14, 2025

Best Process Manufacturing software of 2026: which is right for you?

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Showing 1 - 25 of 110 products

NetSuite is an AI-powered cloud-based business management suite that incorporates ERP, financial management, CRM and eCommerce f...Read more about NetSuite

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Striven is a cloud-based enterprise resource planning (ERP) solution suitable for many industries and organizations of all sizes...Read more about Striven

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Cetec ERP is a manufacturing enterprise resource planning software built for small and medium sized businesses. Cetec ERP's clou...Read more about Cetec ERP

77

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4.73Inventory Management

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Sage X3 is a powerful ERP software solution designed for midsized national and global manufacturers, distributors, and after-sal...Read more about Sage X3

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Intellect is a quality management system designed to support quality processes and regulatory compliance through AI-powered clou...Read more about Intellect QMS AI

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DELMIAworks (formerly IQMS) ERP is developed specifically for SMB and large discrete and batch process manufacturers in the aero...Read more about DELMIAworks

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SyteLine is an enterprise resource planning software created specifically for engineer-to-order, make-to-order, make-to-stock, a...Read more about SyteLine

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QAD Adaptive ERP is a cloud-based enterprise resource planning (ERP) solution designed specifically for manufacturers. It offers...Read more about QAD Adaptive ERP

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Now more than ever before, executives and other leaders in US manufacturing companies need the best information and controls to ...Read more about HYDRA X

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Epicor Advanced MES is a manufacturing execution system that is suited to plastic molders, repetitive manufacturers and those wi...Read more about Epicor Advanced MES

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BatchMaster Software offers process manufacturing software solutions for the food, chemical, nutraceutical and pharmaceutical in...Read more about BatchMaster ERP

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Deacom, an ECI Software Solution, is a comprehensive ERP (Enterprise Resource Planning) platform with a rich set of capabilities...Read more about Deacom ERP

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aACE is a powerful, comprehensive business management solution designed for companies that have outgrown small-business packages...Read more about aACE

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Fishbowl’s powerful inventory management software is designed to help businesses streamline operations, improve accuracy, and sc...Read more about Fishbowl

24

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Acumatica Cloud ERP is a comprehensive business management system. It caters to a variety of industries, such as finance, manufa...Read more about Acumatica Cloud ERP

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Royal 4 Enterprise is an integrated enterprise resource planning (ERP) solution with built-in modules for distribution, manufact...Read more about R4 Enterprise

4.5

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SAP S/4HANA Cloud is a cloud-based and on-premise enterprise resource planning (ERP) solution. It is suitable for small, midsize...Read more about SAP S/4HANA Cloud

20

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Online Computing designs and develops a proprietary ERP software called MasterTools. MasterTools combines all aspects of product...Read more about MasterTools

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20

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MRPeasy is a versatile cloud-based ERP system for small and scaling companies (perfect for up to 200 employees). The software of...Read more about MRPeasy

17

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QT9 ERP is a highly-scalable manufacturing platform for connecting and automating business data from multiple systems into one s...Read more about QT9 ERP

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Datacor ERP (formerly Chempax) is an integrated enterprise resource planning (ERP) and customer relationship management (CRM) ap...Read more about Datacor ERP

12

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SafetyChain's digital plant management platform gives process manufacturers the flexibility to rapidly address urgent challenges...Read more about SafetyChain

7

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4.75Compliance Tracking

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SafetyChain's Worst Rated Features

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IFS Cloud is a composable enterprise software application that orchestrates customers, people, and assets to reduce complexity, ...Read more about IFS Cloud

6

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Visibility ERP is a fully integrated and modern ERP solution designed to meet the unique needs of manufacturers of complex produ...Read more about Visibility ERP

4.3

(9 reviews)

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Connected is a hybrid integrated accounting and enterprise resource planning (ERP) that caters to small and midsize businesses a...Read more about Connected

5.0

(3 reviews)

4

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2345

Buyers Guide

This detailed guide will help you find and buy the right process manufacturing software for you and your business.

Last Updated on October 14, 2025

Gartner defines process manufacturing as, “manufacturing that adds value by performing chemical reactions or physical actions to transform materials, or by extracting, mixing, separating or forming materials in batch or continuous production modes.”

Process manufacturers generally deal with products that pour, such as liquids or powders, and are produced in bulk quantities. It includes industries, such as chemicals, pharmaceuticals, food and beverages and gasoline.

A process manufacturing system must balance four constraints. First, the batch size is constrained by the amount of product on order and stock quantities to be kept on hand. This is particularly key when using materials or creating a product with a limited shelf life. The second constraint is ingredients, as the most limited ingredient determines how much product can be made. Then, there’s packaging inventory, and one of the challenges of process manufacturing is that you need to store the final product in something. The fourth constraint is capacity—or the ability to make a product within the production facility itself.

The critical function of a process manufacturing system is inventory control. One important feature of the inventory system is the ability to manage different units of measurement, for example, determining how many liters of an item are available when it is received in 55 gallon drums. Related to inventory is recipe management, that is, how to alter the formula to make a certain amount or to use available inventory.

On the other hand, a process manufacturing system can be part of an enterprise resource planning (ERP) system, or be part of a best-of-breed set of solutions. It is also possible to integrate with a manufacturing execution system (MES). Accounts payable, accounts receivable, payroll and general ledger are the standard features of these systems. While most installations use on-premises equipment, cloud-based options are also available. Software as a service (SaaS) viability is primarily dictated by the value of installed technology base, but projected maintenance costs of both hardware and software is an important factor as well.

In this buyers guide, we'll cover:

What Is Process Manufacturing Software?

Henry Ford once said, “If you always do what you always did, you’ll always get what you’ve always got.” Manufacturers must heed these words and always strive to make business processes more efficient. Some of the major concerns they face include:

  • Increase in production cost

  • Highly competitive local and global environment

  • Short product life cycle

  • Reduction of profit margins

  • Considerable improvement in quality assurance metrics

Process manufacturing software is designed specifically to manage these complexities. For manufacturers, fulfilling regulatory compliance by tracing ingredients and industrial waste is pivotal. Therefore, across the globe, executives are considering process manufacturing platforms to monitor business processes from end-to-end, that is, from production to delivery.

It is important to note that manufacturing executives can extend process manufacturing capabilities with their existing ERP or MES solutions as an additional module or integration. Furthermore, numerous vendors in the market offer specialized solutions for process manufacturing businesses. Executives should involve all the stakeholders to list out the requisite capabilities in a solution. In addition, buyers should evaluate the suitability and capability of the solution vis-à-vis their requirements before adapting the solution.

Process manufacturing professionals should focus on resolving the following challenges via a process manufacturing platform:

  1. Mitigate product risks and recalls

  2. Increase a product’s time to market

  3. Track and monitor business performance

  4. Accurately forecast product demand and supply chain issues

  5. Achieve regulatory compliance

There are many objectives that can be achieved with the help of a process manufacturing application. Manufacturing organizations with mobile employees and remote workstations should ideally look for solutions that also offer mobile applications.

Common Features of Process Manufacturers Software

In evaluating software, process manufacturers should consider the following functions to meet their unique requirements:

Delivery-driven production

Delivery-driven production matches the batch size to the amount on order plus the quantity to be kept on hand. The system should also verify that all other constraints are met.

Ingredient-driven production

Ingredient-driven production matches the batch size to the available quantities of the ingredients on hand. The system should also verify that all other constraints are met.

Packaging-driven production

Packaging-driven production matches the batch size to the finished amount that can be packaged with materials on hand. The system should also verify that all other constraints are met.

Capacity-driven production

Capacity-driven production matches the batch size to the maximum capacity that the floor can produce. The system should also verify that all other constraints are met.

Critical path production

If the process has stages with delays in between, such as a fermenting stage, then the system can match orders of ingredients to the time when they are required. This can save money in initial production costs by delaying purchases until required but runs the risk of loosing a batch if a required ingredient is not available in time.

Expiration tracking

Both ingredients and products can have limited shelf lives. The system needs to track expired and close-to-end-of-life inventory.

Recipe management

The system should include recipe management, including ingredient substitution. In some cases, ingredients are encoded to keep recipes secret.

Lot management

Each lot must be identified and tracked. The ingredients of each batch must be tied to their individual batch number as well.

Yield variances

The system should track actual yield versus expected yield for each batch. The system should report excessive variance based on user-defined thresholds and indicate if variances are so large that regulating agencies should be notified.

Current Good Manufacturing Practice (cGMP) compliance

cGMP compliance is required for many regulatory agencies at the state and federal levels as well as for insurance purposes. The system should produce required compliance reports.

Units of measure management

The system should convert units of measurement as required for inventory management, order processing, receiving and batch production.

Available to promise, capable to promise

Available to promise (ATP) and capable to promise (CTP) are measures of manufacturing capacity. The system should calculate the ATP and CTP for any stock item, accounting for ingredients on hand and any work in process.

EPA and OSHA compliance

Manufacturers that make, use or have byproducts that are highly hazardous chemicals (HHCs) must comply with the EPA’s Risk Management Program (RMP) and OSHA’s Process Safety Management (PSM) regulations. The system should produce required compliance reports.